VemoHerb Cordyceps

21.80

Dry extract from Cordyceps sinensis CS-4

Maximum endurance and recovery after training *

Supports:

  • muscle recovery after exercises*
  • energy, endurance and stamina*
  • building lean muscle mass*
  • the detoxification of the body*
  • vitality*

 

Description

Benefits Cordyceps

Dry extract from Cordyceps sinensis CS-4

Maximum endurance and recovery after training *

Supports:

  • muscle recovery after exercises*
  • energy, endurance and stamina*
  • building lean muscle mass*
  • the detoxification of the body*
  • vitality*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Production Scheme: VemoHerb Cordycep

VemoHerb® Cordyceps supports cellular uptake of oxygen, which promotes endurance and recovery from physical fatigue. *

Cordyceps sinensis is one of the most famous species of Ascomycota mushroom. Since ancient times, the cordyceps mushroom has been used in traditional medicine as a tonic that energizes the body and vitality. * [1.8]

The properties of VemoHerb® Cordyceps are due to a specific synergistic combination of biologically active substances in its composition: polysaccharides [6], cordycepic acid (D-mannitol) and adenosine. [5.6]

Laboratory Tests: VemoHerb Cordyceps

The adenosine CS-4 in cordyceps contributes to the normal production of ATP (adenosine triphosphate), which is one of the body's main sources of energy. * [5]

 

 

Cordyceps sinensis supports the natural cleaning of muscles from lactic acid accumulated during exercise. The so-called lactate is actually the main cause of muscle fever.

The beneficial effects of Cordyceps sinensis on lactate metabolism, promotes its release from muscles, relieves sensations associated with muscle fever, and thus supports physical endurance. * [1]

The specific polysaccharides in Cordyceps sinensis CS-4 have a positive effect on the immune defense and the liver. * [2,4] They can help the body natural detoxification process. * [2,7] Safe Pure Tested: VemoHerb Cordyceps

The active ingredient adenosine in VemoHerb® Cordyceps supports your vitality and stamina - both physically and mentally. *

It is known for its positive effects on the immune [2,4], cardiovascular [3,4], nervous [3,4] and respiratory systems [4,8]. * Some scientific studies have also shown positive effects of cordyceps on libido. * [4.8] The product is suitable for any athlete or person who plays sports to maintain their health, as it improves endurance and energy during training. *

In addition, VemoHerb® Cordyceps supports:


  • focus and concentration *

  • libido and sexuality of both women and men *

  • natural liver function *


**see the References [1-8] in the Science tab








*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Bioactivesubstanes Cordyceps

Active substances in one capsule:

650.0 mg of cordyceps (mycelium) extract (Cordyceps sinensis CS-4) standardized to at least 30% polysaccharides, 8% cordycepic acid (D-mannitol), 3% adenosine

VemoHerb® Cordyceps is a natural food supplement containing Cordyceps sinensis CS-4 (mycelium), without GMOs or allergens.

The pack contains:
90 vegan capsules

Program dosing Cordyceps

Recommended daily dose


1 capsule 3 times a day

Directions for use:

Take between meals or as directed on the label.

You can find more information on correct consumption and cycle HERE.

 

The product is a food supplement not a medical drug. The product is not a substitute for a varied diet. Do not exceed the recommended daily dose. It is not recommended for pregnant, nursing women and children! Not recommended for people who have functional problems with their thyroid gland.

 

References:


1. Kumar, R., Negi, P. S., Singh, B., Ilavazhagan, G., Bhargava, K., & Sethy, N. K. (2011). Cordyceps sinensis promotes exercise endurance capacity of rats by activating skeletal muscle metabolic regulators.


Both CS supplementation and supplementation concurrent with exercise improved exercise endurance by 1.79- (P<0.05) and 2.9-fold (P<0.01) respectively as compared to placebo rats. CS supplementation concurrent with exercise also increased the swimming endurance by 1.32-fold (P<0.05) over the exercise group. To study the molecular mechanism of the observed effect, we measured the expression levels of endurance responsive skeletal muscle metabolic regulators AMPK, PGC-1α and PPAR-δ as well as endurance promoting and antioxidant genes like MCT1, MCT4, GLUT4, VEGF, NRF-2, SOD1 and TRX in red gastrocnemius muscle. Our results indicate that CS supplementation significantly upregulates the skeletal muscle metabolic regulators, angiogenesis, better glucose and lactate uptake both in exercised and non-exercised rats. We have also observed increased expression of oxidative stress responsive transcription factor NRF-2 and its downstream targets SOD1 and TRX by CS supplementation.
CS supplementation with or without exercise improves exercise endurance capacity by activating the skeletal muscle metabolic regulators and a coordinated antioxidant response. Consequently, CS can be used as a potent natural exercise mimetic.


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2. Chen, P. X., Wang, S., Nie, S., & Marcone, M. Properties of Cordyceps Sinensis: A review.


A great mystique and aura surrounds Cordyceps sinensis (syn.: Cephalosporium sinensis), an endoparasitic fungus which has claims of anti-cancer and anti-aging properties. Much research has been conducted over the years on crude extracts and its bioactivity. More research is now focused on culturing C. sinensis and on isolating and identifying pure compounds novel to C. sinensis in an attempt to alleviate strain on demand for the natural fungi. Several polysaccharides, nucleosides and sterols all have had reports of promoting health both in vitro and in vivo. Specific and novel compounds which are characteristic to C. sinensis are emerging with reports of two new epipolythiodioxopiperazines, gliocladicillins A and B capable of inhibiting growth of HeLa, HepG2 and MCF-7 tumor cells. Exclusive to natural C. sinensis, five constituents of cordysinin (A–E) has also been reported for the first time and has been linked to anti-inflammatory properties. Although it may still be premature to believe these results should translate into pharmaceutical use, there is sufficient evidence to warrant further research.


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3. Zhu, J.-S., Halpern, G. M., & Jones, K. (1998). The Scientific Rediscovery of an Ancient Chinese Herbal Medicine: Cordyceps sinensis Part I.


This review presents Cordyceps sinensis (Berk.) Sacc., a fungus highly valued in China as a tonic food and herbal medicine. The extant records show the continued use of C. sinensis is now centuries old. The major chemical, pharmacological, and toxicological studies on C. sinensis and the various derived, cultured, fermented mycelial products currently in use are reviewed from the English and Chinese literature. Preclinical in vitro and in vivo studies and clinical blinded or open-label trials in to date over 2000 patients are reviewed. These studies show the main activities of the fungus in oxygen-free radical scavenging, antisenescence, endocrine, hypolipidemic, antiatherosclerotic, and sexual function-restorative activities. The safety of the fungus, its effects on the nervous system, glucose metabolism, the respiratory, hepatic, cardiovascular, and immune systems, immunologic disease, inflammatory conditions, cancer, and diseases of the kidney will be reviewed in the second part of this article to be published in the winter issue of this journal.


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4. Zhu, J.-S., Halpern, G. M., & Jones, K. The Scientific Rediscovery of a Precious Ancient Chinese Herbal Regimen: Cordyceps sinensis Part II.


Cordyceps sinensis (Berk.) Sacc. is a time-honored tonic food and herbal medicine in China, where recent research has shown that many of its traditional uses may be viewed from the basis of pharmacological activities. The ongoing exploration of C. sinensis in its wild form and cultured, fermented mycelial products derived from it, are reviewed from English and Chinese literature. Part II concludes the series with a review of C. sinensis in preclinical in vitro and in vivo studies, and open-label and double-blinded clinical trials on the respiratory, renal, hepatic, cardiovascular, immunologic, and nervous systems, and its effects on cancer, glucose metabolism, inflammatory conditions, and toxicological studies. In Part I, which appeared in the Fall 1998 issue of this journal (4(3):289-303), we discussed the effects of C. sinensis on antisenescence, endocrine and sexual functions, atherosclerosis, hyperlipidemia, and free radicals.


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5. Tsai, Y.-J., Lin, L.-C., & Tsai, T.-H. Pharmacokinetics of Adenosine and Cordycepin, a Bioactive Constituent of Cordyceps sinensis in Rat.


Cordycepin is a bioactive constituent of Cordyceps sinensis that has been shown to regulate homeostatic function. As an adenosine analogue, it is possible cordycepin goes through a similar metabolic pathway to that of adenosine. To investigate this hypothesis, a sensitive liquid chromatography with photodiode-array detector (HPLC-PDA) coupled to a microdialysis sampling system was developed to monitor cordycepin and adenosine in rat blood and liver. Other endogenous nucleosides were simultaneously measured to further understand the downstream metabolic pathway. The experiments were divided into six parallel groups for drug administration: (1) normal saline vehicle, (2) adenosine, (3) cordycepin, (4) normal saline + erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA; a potent adenosine deaminase inhibitor), (5) adenosine + EHNA, and (6) cordycepin + EHNA. The pharmacokinetic results suggest that the levels of both adenosine and cordycepin decreased rapidly in blood around 30 min after drug administration. When adenosine was given, the concentrations of adenosine metabolites, hypoxanthinosine and hypoxanthine, increased in rat blood. This phenomenon was inhibited by EHNA pretreatment. An unidentified peak was observed in the blood and liver samples after cordycepin administration. The decline of this unidentified peak paralleled the decreased of the concentration of cordycepin, and it was not observed in the presence of the adenosine deaminase inhibitor. It is concluded that adenosine and cordycepin had short elimination half-lives and high rates of clearance and their biotransformation was suppressed by EHNA.


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6. Liu, Y., Wang, J., Wang, W., Zhang, H., Zhang, X., & Han, C. The Chemical Constituents and Pharmacological Actions of Cordyceps sinensis.


Cordyceps sinensis, also called DongChongXiaCao (winter worm, summer grass) in Chinese, is becoming increasingly popular and important in the public and scientific communities. This study summarizes the chemical constituents and their corresponding pharmacological actions of Cordyceps sinensis. Many bioactive components of Cordyceps sinensis have been extracted including nucleoside, polysaccharide, sterol, protein, amino acid, and polypeptide. In addition, these constituents' corresponding pharmacological actions were also shown in the study such as anti-inflammatory, antioxidant, antitumour, antiapoptosis, and immunomodulatory actions. Therefore can use different effects of C. sinensis against different diseases and provide reference for the study of Cordyceps sinensis in the future.


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7. Li, S. P., Li, P., Dong, T. T. X., & Tsim, K. W. K. Anti-oxidation activity of different types of natural Cordyceps sinensis and cultured Cordyceps mycelia.


Cordyceps, one of the well-known traditional Chinese medicines, consists of the dried fungus Cordyceps sinensis growing on the larva of the caterpillar. It is commonly used for the replenishment of body health. One of the known pharmacological effects is its anti-oxidation activity. However, there is a great variation of the quality in different sources of Cordyceps. Here, the water extracts of various sources of natural C. sinensis and cultured Cordyceps mycelia were analyzed for their anti-oxidation activity by using three different assay methods such as the xanthine oxidase assay, the induction of hemolysis assay and the lipid peroxidation assay. The results showed that Cordyceps, in general, possesses a strong anti-oxidation activity in all assays tested. However, both natural and cultured Cordyceps showed the lowest inhibition in the lipid peroxidation when compared with the other two assay methods. The cultured Cordyceps mycelia had equally strong anti-oxidation activity as compared to the natural Cordyceps. Besides, the anti-oxidation activities were increased to 10-30 folds in the partially purified polysaccharide fractions from the cultured Cordyceps mycelia, which suggested that the activity could be derived partly from Cordyceps polysaccharides.


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8. Shashidhar, M. G., Giridhar, P., Udaya Sankar, K., & Manohar, B. Bioactive principles from Cordyceps sinensis: A potent food supplement – A review.


Cordyceps sinensis (CS) is a well-known entamophagus fungus, naturally distributed in the Tibetan Plateau of Asia and Himalayas. Recently this synonym is transferred to Ophiocordyceps by both scientific and non-scientific communities. It is widely used as a tonic and medicinal food in traditional Chinese medicine (TCM), as it possess wonderful health benefits. To support its functional attributes, various investigations have been carried out to find out its adaptogenic, aphrodisiac, anti-oxidant, anti-aging, neuroprotective, nootropic, immunomodulatory, anti-cancer and hepatoprotective role. Its fruiting portion as well as the larvae possesses potent bio-active fractions and their composition almost found to be similar in both. The bioactive principles are nucleosides, exo-polysaccharides, sterols and, proteins, among others. Among nucleosides, adenosine and cordycepin are the major biochemical markers. Further, different types of solvent extracts and their mixtures exhibit wide range of pharmacological activities, while the water and methanol extracts with the richest sources of nucleosides and polysaccharides also show wide range of pharmacological activities. This review gives a panoramic view of potential health benefits of various classes of bio-active fractions along with the need for sustainable management of CS for human wellness.


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1 review for VemoHerb Cordyceps

  1. M. Pl

    It’s one of the best supplements I ever tried for muscle recovery after exercises!

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