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Ecdysterone Before and After – Its Effects and Benefits
Ecdysterone Before and After – Its Effects and Benefits

Are you a fitness enthusiast looking for ways to build muscle and improve your performance? Ecdysterone has gained traction as a potential supplement for athletes and bodybuilders.
This article dives into the current research on ecdysterone, exploring its potential benefits, side effects, and important considerations before you try it.
We’ll also discuss how ecdysterone stacks up against similar supplements like turkesterone. So, is ecdysterone the next big thing in sports supplements? Read on to find out!
What Is Ecdysterone?
Ecdysterone is a naturally occurring steroid hormone found in insects, some crustaceans, and a variety of plants [1]. In insects, it plays a critical role in processes such as molting and metamorphosis [2].
Ecdysterone is one of the ecdysteroid hormones that are responsible for the growth of plants or insects. Ecdysteroids share structural similarities with testosterone [3], and those exact properties spiked the interest of researchers who have begun to look for an answer to whether the hormone can have an anabolic effect on humans.
As of now, some athletes and bodybuilders use ecdysterone supplements because it is believed they can support building muscle mass and improve performance. But is that really the case? What are the actual effects of ecdysterone on the human body?
Effects of Ecdysterone
The effects of ecdysterone on humans are a topic of ongoing research with some promising but inconclusive results. Here’s a breakdown of what we know so far:
Muscle Growth and Performance*
The research suggests that there might be something to back up claims that the hormone can be an effective bodybuilding supplement.
For example, in an in vitro study done on skeletal muscle cells, it was proven that the phytoecdysteroids hormones (which are structurally similar or identical to ecdysterone): “produce a range of effects in mammals, including increasing growth and physical performance.” [4] Phytoecdysteroids increased protein synthesis by up to 20%.
In a 10-week study of strength training of young men [5], the participants were administered different doses of ecdysterone-containing supplements. Researchers analyzed the blood and urine samples, looking for potential performance-enhancing biomarkers. The results of this study were very promising. What researchers discovered was that:
- Supplements caused significant increases in muscle mass (the group taking the highest dose noted two kilograms of muscle gain).*
- Ecdysterone was also responsible for notable increases in one-repetition bench press performance. *
- Supplements have not had any adverse effects on liver and kidney function*.
- Participants in the placebo group noted smaller muscle gain than those who were administered ecdysterone supplements. *
However, this particular study received some criticism, primarily relating to the authors of the paper using bio-impedance markers to reach their conclusions, which is not an accurate enough measure for these results to be fully reliable.
There were also studies conducted on mice and rats [6], which offered similar results. Still, as of now, we don’t have enough data to categorically prove the muscle and performance enhancing effect of ecdysterone-containing supplements.
Taking everything we just talked about into account, there might be some merit to including such supplements in your regimen, though. however, the data we have now shows the good potential of this hormone in supporting athletes by increasing muscle mass and endurance*.
Other Effects
Some other talked about effects of ecdysterone include improved blood flow*. However, there’s a need for more research to verify those claims.
All of this goes to show that there’s still a lot to learn and confirm about ecdysterone and how it can affect athletes. From where we’re looking today, it seems that the hormone may be potentially beneficial to support a healthy lifestyle and support reducing stress*.
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Ecdysterone Before and After – Ecdysterone Results
The results of ecdysterone-based supplements may vary between individuals. While some athletes report seeing noticeable changes in their muscle build and performance when administering the supplements, that is not the case for every person who decides to try ecdysterone supplementation.
Before you include ecdysterone into your regimen, it might be helpful to read and watch reviews of other bodybuilders to find out about their personal experiences with the supplements and strategies that worked for them.
From analyzing some of the ecdysterone supplement reviews online [9], we can name a few recurring trends. Namely:
- Many reviewers mention seeing increased muscle mass, with some claiming significant gains in a short period after introducing ecdysterone.*
- Several reviewers noted a boost in strength and improvement in the incline bench press.*
- Some users reported experiencing better endurance while taking ecdysterone.*
- Some also mentioned faster recovery as a benefit.*
It’s important to take those claims as what they are – anecdotal evidence that is based solely on the personal experiences of those individuals. Results may vary depending on the brand of the supplement, particular administration schedule, genetics, diet, and training.
Benefits of Ecdysterone
Ecdysterone shows potential benefits for muscle building and athletic performance, but the evidence is still developing.
On the list of potential benefits of ecdysterone, we can find:
- Muscle growth*
- Improved strength and performance*
- Support in post-workout recovery*
Before considering ecdysterone supplements, it’s crucial to talk to your doctor to discuss the potential risks and benefits specific to you.
Potential Side Effects
Ecdysterone is a relatively new supplement, and research on its long-term safety is limited. While generally considered safe, there are some potential side effects to be aware of.
If you’re considering taking ecdysterone, it might be valuable to discuss it with your doctor first. They can help you weigh the potential risks and benefits based on your individual health and medical history.

Ecdysterone – Important Considerations
We’re the biggest proponents of reaping the benefits of what nature has in store for us. Using ecdysterone-based supplements could be a good strategy to achieve your athletic goals. However, the key is to go into any regimen fully informed.
Here are some of the most important considerations when talking about or using ecdysterone.
- Limited Research: Most studies conducted on ecdysterone and how it affects humans are small-scale it’s crucial to be aware of the fact that we still need more research done on the topic to prove those claims.
- Regulation: Ecdysterone supplements are not regulated by the FDA in the US, so quality and purity can vary greatly. It’s crucial to be mindful of which suppliers you are buying your supplements from. Always do your research and choose the store/brand that is transparent about their products and practices.
- Individual Results: The effectiveness of these supplements may vary depending on factors like genetics and training regimen. Some people report achieving great results with ecdysterone supplements, but that might not be the case for everyone. Managing your expectations is an important part of finding the right bodybuilding supplements for you.
- Holistic Approach: Sportsmen who take ecdysterone often emphasize the importance of factors such as good diet and exercise in the bodybuilding process. Ecdysterone offers the most benefits when paired with training and proper nutrition. The holistic approach is key here.
Is It Necessary To Cycle Ecdysterone?
There isn’t a clear consensus on whether cycling ecdysterone is necessary. On the one hand, unlike traditional steroids, ecdysterone doesn’t appear to suppress testosterone levels, which is why cycling might not be necessary [11].
Still, many users recommend cycling, adhering to different cycling schedules (commonly, 8-12 weeks).
Ecdysterone or Turkesterone – Which One is Better?
Truth be told, it is difficult to determine which of the two might be better for bodybuilding and performance enhancement.
Ecdysterone and turkesterone share some crucial similarities: both may promote muscle growth and increase muscle protein synthesis.* They are not considered anabolic-androgenic steroids, which means they are often associated with fewer negative side effects [12].
Interestingly, due to the fact that ecdysterone and turkesterone are natural extracts with fairly similar molecular structures, they can be used in tandem without risking side effects [13].
We don’t have enough research to conclude which supplement is more effective for muscle growth and other bodybuilding goals, so it might be the case of trial and error or combining the two to check which strategy offers you the best end results.
Quality Ecdysterone Supplements
Ecdysterone supplements are not regulated by the FDA in the US. This means the quality and purity of supplements can vary. It’s this much more important to trust a good ecdysterone supplier.
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Ecdysterone Before and After – Final Thoughts
Ecdysterone shows promise as a natural supplement for muscle growth and performance enhancement, but research is still being done on this subject*. While it may offer some benefits with fewer side effects than traditional steroids, there are important considerations.
The quality and purity of ecdysterone supplements can vary greatly depending on the brand and supplier. Individual results may differ, too.
Before jumping on the ecdysterone bandwagon, consult your doctor to discuss the potential risks and benefits specific to you. They can help you determine if ecdysterone fits into your overall training and supplement plan.
And remember – building muscle and improving athletic performance takes dedication, proper diet, and consistent effort. Supplements can potentially play a supporting role, but they shouldn’t be a substitute for a solid training plan and healthy lifestyle.
Sources:
- Shuvalov O, Fedorova O, Tananykina E, Gnennaya Y, Daks A, Petukhov A, Barlev NA. An Arthropod Hormone, Ecdysterone, Inhibits the Growth of Breast Cancer Cells via Different Mechanisms. Front Pharmacol. 2020 Oct 30;11:561537. doi: 10.3389/fphar.2020.561537. PMID: 33192507; PMCID: PMC7663021.
- Kannangara JR, Mirth CK, Warr CG. Regulation of ecdysone production in Drosophila by neuropeptides and peptide hormones. Open Biol. 2021 Feb;11(2):200373. doi: 10.1098/rsob.200373. Epub 2021 Feb 17. PMID: 33593157; PMCID: PMC8103234.
- “Research Breakdown on Ecdysteroids – Examine.” Examine.com, examine.com/supplements/ecdysteroids/research/.
- Gorelick-Feldman J, Maclean D, Ilic N, Poulev A, Lila MA, Cheng D, Raskin I. Phytoecdysteroids increase protein synthesis in skeletal muscle cells. J Agric Food Chem. 2008 May 28;56(10):3532-7. doi: 10.1021/jf073059z. Epub 2008 Apr 30. PMID: 18444661.
- Isenmann E, Ambrosio G, Joseph JF, Mazzarino M, de la Torre X, Zimmer P, Kazlauskas R, Goebel C, Botrè F, Diel P, Parr MK. Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans. Arch Toxicol. 2019 Jul;93(7):1807-1816. doi: 10.1007/s00204-019-02490-x. Epub 2019 May 23. PMID: 31123801.
- Dinan, L., & Lafont, R. (2006). Effects and applications of arthropod steroid hormones (ecdysteroids) in mammals. Journal of Endocrinology, 191(1), 1-8. Retrieved Mar 21, 2024, from https://doi.org/10.1677/joe.1.06900
- Yang L, Pan J. Therapeutic Effect of Ecdysterone Combine Paeonol Oral Cavity Direct Administered on Radiation-Induced Oral Mucositis in Rats. Int J Mol Sci. 2019 Aug 3;20(15):3800. doi: 10.3390/ijms20153800. PMID: 31382644; PMCID: PMC6695810.
- Shakhmurova, G A, et al. “Immunomodulating and Antistress Activity of Ecdysterone and Turkesterone under Immobilization-Induced Stress Conditions in Mice.” Pharmaceutical Chemistry Journal, vol. 44, no. 1, 1 May 2010, pp. 7–9, https://doi.org/10.1007/s11094-010-0387-8. Accessed 22 Mar. 2024.
- Risley, Kyle. “Ecdysterone before & After: 5 Reviews with Results (2024).” Lift Vault, 7 Jan. 2023, liftvault.com/nutrition/ecdysterone-before-after/.
- The Spinach Compound That Can Support Muscle Mass.” Dr. Axe, draxe.com/nutrition/ecdysterone/#Risks_and_Side_Effects.
- “The Ultimate Ecdysterone Supplements Guide: Its Uses, Side Effects & Benefits.” Prohormones, pro-hormones.co.uk/blogs/news/a-guide-to-ecdysterone.
- Risley, Kyle. “Turkesterone vs. Ecdysterone: A Research Comparison (2024).” Lift Vault, 26 Dec. 2021, liftvault.com/nutrition/turkesterone-vs-ecdysterone/.
- “Ecdysterone vs Turkesterone: Which Is Better?” Prohormones, pro-hormones.co.uk/blogs/news/ecdysterone-vs-turkesterone.
