VemoHerb Artemisia

9.90

  • Supports the immune system and healthy lifestyle
  • Helps blood circulation
  • Supports the body’s liver function
  • Promotes cellular repair and healthy aging

Description

Dry extract from Artemisia annua L.

  • Supports the immune system
  • Supports the overall well-being and healthy life style
  • Has positive antibacterial properties
  • Has positive antioxidant properties
  • Helps blood circulation
  • Supports the body’s liver function
  • Promotes cellular repair and healthy aging
  • Helps maintain a healthy balance of good bacteria in natural way

The product is a food supplement not a medical drug. The product is not a substitute for a varied diet. Do not exceed the recommended daily dose. It is not recommended for pregnant, nursing women and children!

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

How and Why It Works?


Artemisia annua L., also known as Sweet wormwood, has a long year history in traditional Chinese medicine to support the immune system in the fight against unbeneficial organisms. The properties of VemoHerb® Artemisia are mainly attributed to the presence of the active ingredient artemisinin in the extract. [1] The plant also contains rich bouquet of biologically active substances: terpenes, flavonoids, polysaccharides, which in combination with artemisinin contribute to the therapeutic effect of the product. [1,2]

The discovery of the active substance artemisinin won a Nobel Prize in Physiology or Medicine to the key contributors of the research. [3] This has put the Artemisia annua extract into the center of numerous research activities, allowing for its benefits to be widely studied.

VemoHerb® Artemisia is a powerful antioxidant and supports the overall health and well-being. It is a highly beneficial dietary supplement that supports the body rid itself from toxins, the strengthening of the immune system and general health after exhaustion in natural way. [2, 4]

The artemisinin is naturally occurring compound, which is involved in the regeneration of reactive oxygen species, maintenance of the immune system functions, and angiogenesis inhibition. [2, 5] Thus, the extract from Artemisia annua is considered a very powerful aid in keeping the organism in a balanced and healthy state.

Studies show that Artemisia annua also has antibacterial and antifungal properties. The extract has been tested on a wide range of bacteria, such as E. coli and S. aureus, and was shown to have very good inhibition capability. [6,7] In addition, Artemisia annua is reported to have anti-inflammatory and hepatoprotective effect, due to the synergistic action of all active compounds in the extract. [2, 8]
VemoHerb® Artemisia supports the healthy life style and helps in cases where strong immune system is needed. It helps the body to maintain normal levels of blood sugar in a natural way. [9]

VemoHerb® Artemisia is recommended for:

  • A strong immune system

  • Improved blood circulation

  • Antiviral and antibacterial purposes

  • Improved overall health status

    How and Why It Works?


    Artemisia annua L., also known as Sweet wormwood, has a long year history in traditional Chinese medicine to support the immune system in the fight against unbeneficial organisms. The properties of VemoHerb® Artemisia are mainly attributed to the presence of the active ingredient artemisinin in the extract. [1] The plant also contains rich bouquet of biologically active substances: terpenes, flavonoids, polysaccharides, which in combination with artemisinin contribute to the therapeutic effect of the product. [1,2]

    The discovery of the active substance artemisinin won a Nobel Prize in Physiology or Medicine to the key contributors of the research. [3] This has put the Artemisia annua extract into the center of numerous research activities, allowing for its benefits to be widely studied.

    VemoHerb® Artemisia is a powerful antioxidant and supports the overall health and well-being. It is a highly beneficial dietary supplement that supports the body rid itself from toxins, the strengthening of the immune system and general health after exhaustion in natural way. [2, 4]

    The artemisinin is naturally occurring compound, which is involved in the regeneration of reactive oxygen species, maintenance of the immune system functions, and angiogenesis inhibition. [2, 5] Thus, the extract from Artemisia annua is considered a very powerful aid in keeping the organism in a balanced and healthy state.

    Studies show that Artemisia annua also has antibacterial and antifungal properties. The extract has been tested on a wide range of bacteria, such as E. coli and S. aureus, and was shown to have very good inhibition capability. [6,7] In addition, Artemisia annua is reported to have anti-inflammatory and hepatoprotective effect, due to the synergistic action of all active compounds in the extract. [2, 8]
    VemoHerb® Artemisia supports the healthy life style and helps in cases where strong immune system is needed. It helps the body to maintain normal levels of blood sugar in a natural way. [9]

    VemoHerb® Artemisia is recommended for:

    • A strong immune system

    • Improved blood circulation

    • Antiviral and antibacterial purposes

    • Improved overall health status










*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Active substances in one capsule


200,0 mg dry extract from Artemisia annua L., standardized at min 3% artemisinin

 

Recommended daily dose


Take 1 capsule 2-3 times a day

Directions for use


Take between the meals or as directed on the label.
More information about the right intake and cycling, you can find HERE.



The pack contains


60 vegan capsules

References to How and Why It Works:


1. Septembre-Malaterre, A., Lalarizo Rakoto, M., Marodon, C., Bedoui, Y., Nakab, J., Simon, E., Hoarau, L., Savriama, S., Strasberg, D., Guiraud, P., Selambarom, J. and Gasque, P., 2020. Artemisia annua, a Traditional Plant Brought to Light. International Journal of Molecular Sciences, 21(14), p.4986.


The family Asteraceae comprises a wide number of genera, of which the genus Artemisia is one of the largest and most widely distributed worldwide [1]. The genus Artemisia L. is heterogeneous and consists of over 500 species widely geographically distributed in all continents except Antarctica. The genus acclimatizes to any environment, from sea level to high altitudes [2]. However, most of Artemisia species grow preferentially in the Northern Hemisphere and at a lower level in the Southern Hemisphere [3,4]. Species of this genus can be perennial, biennial or annual grasses, shrubs or bushes that are generally aromatic, with erect or ascending stems. The leaves of these plants are alternate, often divided, rarely whole and with smooth edges. The origin of the scientific name of the genus Artemisia stems from two major interpretations. The first proposition addresses the name “Artemisia” from the Greek goddess “Artemis” (Diana for the Romans), Zeus’s daughter and Apollo’s sister, who was considered the protector of the wild animals and goddess of the hunt. The second interpretation assigns the origin of the name to the King of Caria’s (Mausolus) sister and wife Artemisia, who was crowned Queen after her husband’s death. The genus Artemisia is commonly known as “wormwood”. Wormwood, though, strictly speaking, refers to Artemisia absinthium L., which is one of the most common and well-known species of the genus [5]. The type species of the genus Artemisia is the Artemisia vulgaris [6]. Apart from Artemisia annua L., other very well-known species of the genus include Artemisia absinthium, Artemisia abrotanum and Artemisia afra. These species were used to treat fever and malaria, respectively, in China, Europe and Africa [7]. Artemisia verlotiorum Lamotte was introduced to, and is still present in, the Mascarene Island


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2. Zyad, A., Tilaoui, M., Jaafari, A., Oukerrou, M. and Mouse, H., 2017. More insights into the pharmacological effects of artemisinin. Phytotherapy Research, 32(2), pp.216-229.


Artemisinin is one of the most widely prescribed drugs against malaria and has recently received increased attention because of its other potential biological effects. The aim of this review is to summarize recent discoveries of the pharmaceutical effects of artemisinin in basic science along with its mechanistic action, as well as the intriguing results of recent clinical studies, with a focus on its antitumor activity. Scientific evidence indicates that artemisinin exerts its biological activity by generating reactive oxygen species that damage the DNA, mitochondrial depolarization, and cell death. In the present article review, scientific evidence suggests that artemisinin is a potential therapeutic agent for various diseases. Thus, this review is expected to encourage interested scientists to conduct further preclinical and clinical studies to evaluate these biological activities.


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3. Su, X. and Miller, L., 2015. The discovery of artemisinin and the Nobel Prize in Physiology or Medicine. Science China Life Sciences, 58(11), pp.1175-1179


The discovery of artemisinin dramatically changes the landscape to combat malaria and leads to a paradigm shift in antimalarial drug development. According to a recent WHO report, 97 countries have ongoing malaria transmission, and an estimated 3.4 billion people are at risk of malaria, of whom ~1.2 billion are at high risk [1]. Artemisinin represents a new class of antimalarial drugs, which leads to two paradigm shifts in antimalarial research and therapy. The first one is the change from quinoline-based antimalarial drugs to artemisinin-based therapies due to the emergence of parasites resistant to quinoline drugs. Currently, ACTs are the drugs recommended by WHO for treating the deadly Plasmodium falciparum infections and are being used worldwide.


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4. Wang, 2011. The anti-malarial artemisinin inhibits pro-inflammatory cytokines via the NF-κB canonical signaling pathway in PMA-induced THP-1 monocytes. International Journal of Molecular Medicine, 27(2).


Several kinds of sesquiterpene lactones have been proven to inhibit NF-κB and to retard atherosclerosis by reducing lesion size and changing plaque composition. The anti-malarial artemisinin (Art) is a pure sesquiterpene lactone extracted from the Chinese herb Artemisia annua (qinghao, sweet wormwood). In the present study, we demonstrate that artemisinin inhibits the secretion and the mRNA levels of tumor necrosis factor (TNF)-α, interleukin (IL)-1ß, and IL-6 in a dose-dependent manner in phorbol 12-myristate 13-acetate (PMA)-induced THP-1 human monocytes. We also found that the NF-κB specific inhibitor, Bay 11-7082, inhibited the expression of these pro-inflammatory cytokines, suggesting that the NF-κB pathway may be involved in the decreased cytokine release. At all time-points (1-6 h), artemisinin impeded the phosphorylation of IKKα/ß, the phosphorylation and degradation of IκBα and the nuclear translocation of the NF-κB p65 subunit. Additionally, artemisinin inhibited the translocation of the NF-κB p65 subunit as demonstrated by confocal laser scanning microscopic analysis and by NF-κB binding assays. Our data indicate that artemisinin exerts an anti-inflammatory effect on PMA-induced THP-1 monocytes, suggesting the potential role of artemisinin in preventing the inflammatory progression of atherosclerosis.


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5. Wartenberg, M., Wolf, S., Budde, P., Grünheck, F., Acker, H., Hescheler, J., Wartenberg, G. and Sauer, H., 2003. The Antimalaria Agent Artemisinin Exerts Antiangiogenic Effects in Mouse Embryonic Stem Cell-Derived Embryoid Bodies. Laboratory Investigation, 83(11), pp.1647-1655.


Artemisinin is widely used as an agent to treat malaria; the possible antiangiogenic effects of this compound are unknown. In the present study, the antiangiogenic effects of artemisinin were investigated in mouse embryonic stem cell-derived embryoid bodies, which are a model system for early postimplantation embryos and which efficiently differentiate capillaries. Artemisinin dose dependently inhibited angiogenesis in embryoid bodies and raised the level of intracellular reactive oxygen species. Furthermore impaired organization of the extracellular matrix component laminin and altered expression patterns of matrix metalloproteinases 1, 2, and 9 were observed during the time course of embryoid body differentiation. Consequently accelerated penetration kinetics of the fluorescent anthracycline doxorubicin occurred within the tissue, indicating increased tissue permeability.

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6. Tajehmiri, A., Issapour, F., Moslem, M., Lakeh, M. and Kolavani, M., 2014. In vitro antimicrobial activity of artemisia annua leaf extracts against pathogenic bacteria. Advanced Studies in Biology, 6, pp.93-97.


In recent years, the usage of plant materials as food supplement and as alternative medicine has increased. Medicinal herbs are a rich source of antimicrobial agents. In this investigation, antimicrobial effects of leaf methanol and ethanol extracts of Artemisia annua against Staphylococcus aureus PTCC 1431, Salmonella enterica PTCC 1231, Klebsiella pneumonia PTCC 1053, Shigella dysenteriae PTCC 1188 and Escherichia coli PTCC 1399 were studied, using well diffusion method. Methanol and ethanol extracts obtained from leaves of A. annua exhibited antimicrobial activity against test microorganisms. The methanol extract of A. annua showed high inhibition of the growth of S. aureus PTCC 1431, S. enterica PTCC 1231 with inhibitory, 16.5 and 15.5 mm, with average 13.7 mm. The results indicate the fact that extracts of A. annua could be effectively used against diseases caused by selected human pathogens.


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7. Mirbehbahani, F., Hejazi, F., Najmoddin, N. and Asefnejad, A., 2020. Artemisia annua L. as a promising medicinal plant for powerful wound healing applications. Progress in Biomaterials, 9(3), pp.139-151


Artemisia annua L. has been utilized for the first time in a nanofibrous wound dressing composition. The extract of this valuable plant provides anti-inflammatory, anti-bacterial and anti-microbial properties which can be considered as a promising medicinal component in therapeutic applications. In the present work, Artemisia annua L. was picked up from Gorgan forest area of Northern Iran and its extract was prepared by methanol as the extraction solvent. In the fabrication of wound dressing, Artemisia annua L. extract was mixed with gelatin and a nanofibrous structure was formed by electrospinning technique. To have a wound dressing with acceptable stability and optimum mechanical properties, this biologically active layer was formed on a PCL nanofibrous base layer. The fabricated double-layer wound dressing was analyzed chemically, structurally, mechanically and biologically.


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8. Meshnick, S., 2002. Artemisinin: mechanisms of action, resistance and toxicity. International Journal for Parasitology, 32(13), pp.1655-1660.


Artemisinin and its derivatives are widely used throughout the world. The mechanism of action of these compounds appears to involve the heme-mediated decomposition of the endoperoxide bridge to produce carbon-centred free radicals. The involvement of heme explains why the drugs are selectively toxic to malaria parasites. The resulting carbon-centred free radicals are alkylate heme and proteins, one of which is the translationally controlled tumour protein. Clinically relevant artemisinin resistance has not been demonstrated, but it is likely to occur since artemisinin resistance has been obtained in laboratory models. At high doses, artemisinin can be neurotoxic but toxicity has not been found in clinical studies. The mechanism of neurotoxicity may be similar to the mechanism of action.


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9. Kefale, A. and Dabe, N., 2017. Antidiabetic effects of artemisia species: A systematic review. Ancient Science of Life, 36(4), p.175.


The metabolic dysregulation associated with DM causes secondary pathophysiological changes in multiple organ systems that impose a tremendous burden on the individual with diabetes and on health care systems.[2] Diabetes mellitus is a global health crisis, which has been persistently affecting humanity, irrespective of the socioeconomic profile and geographic location of the population.[3,4] Despite advances in understanding and management of this metabolic disorder, the rate of morbidity and mortality due to this disorder is increasing every year. Globally, an estimated 415 million adults were living with DM in 2015 and this figure is expected to increase to 642 million by the year 2040.


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