Support your libido with dry extracts from Bulgarian Tribulus, Turnera Diffusa (Damiana), Ginkgo biloba and Nettle root.*
How and Why It Works?
VemoHerb® Men’s Formula is very suitable for supporting the sexual health of middle-aged men, used in cases of low sexual activity caused by physical overwork and stress.* [1 – 7]
The combination of active ingredients is especially selected, complementing and helping each other synergistically in physiological aspect so that the properties and the application of the supplement is endorsed.
The extract from Turnera Diffusa (Damiana) promotes the blood flow in the organs in the pelvis, and supports the sexual desire.* [2, 6, 8] These properties of the Damiana are strengthened by the ginkgo flavone glycosides in the extract from Ginkgo biloba, the hydroxycoumarins, sterols and zinc in the extract from Urtica dioica, and the furostanol saponin protodioscin in the Bulgarian Tribulus terrestris extract.
The ginkgo flavone glycosides influence positively the male sex hormones and together with the terpenoids, support the blood circulation in the limbs.* They help the activity of the cardio-vascular and nervous systems and have positive influence in cases of physical overwork and stress.* [3, 9]
The hydroxycoumarin derivatives, sterols and zinc support the natural production of testosterone and influence positively the prostate health.* The properties of the Urtica dioica extract to encourage sexual desire are additionally empowered by the Turnera Diffusa in the dietary supplement blend.* [2, 3, 6, 8]
Protodioscin in combination with the other furostanol saponins from the Bulgarian Tribulus terrestris extract positively influence the hormonal balance (especially of sex hormones) in both sexes.*[1, 10, 11, 12] In women, they work on the levels of pregnenolone, progesterone, and estrogens and enhance the libido, thus in general supporting the physical and psycho-emotional health.*  Together with the Damiana, these biologically active substances help the natural hormone production, particularly testosterone, enhance sexual desire and show aphrodisiac properties.
VemoHerb Men’s Formula is a very effective way of improving sexual relations, which are an important part of living a normal life.* [2 – 6, 13]
The pack contains
25 vegan capsules
Active substances in one capsule
200,0 mg dry extract from Bulgarian Tribulus terrestris containing 60% furastanol saponins determined as protodioscin; 250,0 mg dry extract from roots of Turnera Diffusa (Damiana) 10:1; 130,0 mg dry extract from leaves of Ginkgo biloba with not less than 24% ginkgo flavone glycosides and 100,0 mg dry extract from roots of Urtica dioica containing min 5% scopoletin
Recommended daily dose
Take 1-4 capsules a day
Directions for use
1 capsule, an hour before sex
The product is a food supplement not a medical drug. The product is not a substitute for a varied diet. Do not exceed the recommended daily dose. It is not recommended for pregnant, nursing women and children!
1. Gauthaman, K. and Ganesan, A. – The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction – an evaluation using primates, rabbit and rat. Phytomedicine (2008) 15: 44.
Hormonal effects of Tribulus terrestris (TT) were evaluated in primates, rabbit and rat to identify its usefulness in the management of erectile dysfunction (ED). TT extract was administered intravenously, as a bolus dose of 7.5, 15 and 30 mg/kg, in primates for acute study. Rabbits and normal rats were treated with 2.5, 5 and 10mg/kg of TT extract orally for 8 weeks, for chronic study. In addition, castrated rats were treated either with testosterone cypionate (10mg/kg, subcutaneously; biweekly for 8 weeks) or TT orally (5mg/kg daily for 8 weeks). Blood samples were analyzed for testosterone (T), dihydrotestosterone (DHT) and dehydroepiandrosterone sulphate (DHEAS) levels using radioimmunoassay. In primates, the increases in T (52%), DHT (31%) and DHEAS (29%) at 7.5mg/kg were statistically significant. In rabbits, both T and DHT were increased compared to control, however, only the increases in DHT (by 30% and 32% at 5 and 10mg/kg) were statistically significant. In castrated rats, increases in T levels by 51% and 25% were observed with T and TT extract respectively that were statistically significant. TT increases some of the sex hormones, possibly due to the presence of protodioscin in the extract. TT may be useful in mild to moderate cases of ED.
2. Sabna Kotta, Shahid H. Ansari, Javed Ali – Exploring scientifically proven herbal aphrodisiacs, Departments of Pharmaceutics,Pharmacognosy and Phytochemistry, Jamia Hamdard, Hamdard Nagar, New Delhi, India, (2013).
Procreation was an important moral and religious issue and aphrodisiacs were sought to ensure both male and female potency. Sexual dysfunction is an inability to achieve a normal sexual intercourse, including premature ejaculation, retrograded, retarded or inhibited ejaculation, erectile dysfunction, arousal difficulties (reduced libido), compulsive sexual behavior, orgasmic disorder, and failure of detumescence. The introduction of the first pharmacologically approved remedy for impotence, Viagra (sildenafil) in 1990s caused a wave of public attention, propelled in part by heavy advertising. The search for such substances dates back millennia. An aphrodisiac is an agent (food or drug) that arouses sexual desire. The hunt for natural supplement from medicinal plants is being intensified mainly because of its fewer side effects. In this review, we have mentioned the pharmacologically tested (either in man or animal or in both) aphrodisiac plants, which have claimed for its uses.
3. Jameel Mohd, Ansari Javed Akhtar, Ali Abuzer, Ahamad Javed, Ali M., Tamboli Ennus – Pharmacological scientific evidence for the promise of tribulus terrestris
The usage of plants, plant extracts or plant-derived pure chemicals for disease management, become a therapeutic modality, which has stood the test of time. In the present review, we focus on pharmacological profile (in tabular form) of Tribulus terrestris L., apart from Phytochemistry, Taxonomy and Traditional uses. Data were located, selected and extracted from SCI database, Medline, Pubmed, Highwire and Google Scholar. Fruits and seeds of Tribulus terrestris L., (Zygophyllaceae) are of immense importance in oriental medicine because they are used as an aphrodisiac, diuretic and anthelmintic, as well as to treat coughs and kidney failure. Tribulus terrestris L. has reported to have antimicrobial, antihypertension, diuretic, antiacetylcholine, haemolytic activity, spermatogenesis and libido enhancer, antitumor activity and effects on cardiovascular system. Furostanol and spirostanol saponins, flavonoid glycosides, alkaloids, steroidal saponins named terrestrosins A, B, C, D and E, F-gitonis, gitnin and amides have been reported to occur in Tribulus terrestris L. Traditionally T. terrestris is used in folk medicine as a tonic, aphrodisiac, palliative, astringent, stomachic, antihypertensive, diuretic, lithon-triptic, cordial drug and urinary anti-infective. The ash of the whole plant is good for external application in rheumatic-arthritis.
(PDF) Pharmacological scientific evidence for the promise of Tribulus terrestris.
4. Saurabh Chhatre, Tanuja Nesari, Gauresh Somani, Divya Kanchan, and Sadhana Sathaye – Phytopharmacological overview of Tribulus terrestris
Tribulus terrestris (family Zygophyllaceae), commonly known as Gokshur or Gokharu or puncture vine, has been used for a long time in both the Indian and Chinese systems of medicine for treatment of various kinds of diseases. Its various parts contain a variety of chemical constituents which are medicinally important, such as flavonoids, flavonol glycosides, steroidal saponins, and alkaloids. It has diuretic, aphrodisiac, antiurolithic, immunomodulatory, antidiabetic, absorption enhancing, hypolipidemic, cardiotonic, central nervous system, hepatoprotective, anti-inflammatory, analgesic, antispasmodic, anticancer, antibacterial, anthelmintic, larvicidal, and anticariogenic activities. For the last few decades or so, extensive research work has been done to prove its biological activities and the pharmacology of its extracts. The aim of this review is to create a database for further investigations of the discovered phytochemical and pharmacological properties of this plant to promote research. This will help in confirmation of its traditional use along with its value-added utility, eventually leading to higher revenues from the plant.
5. A. Adimoelja – Phytochemicals: modern views and breakthrough in traditional herbal management of sexual dysfunctions
Traditional herbs have been a revolutionary breakthrough in the management of erectile dysfunction and have become known world-wide as an ‘instant’ treatment. The modern view of the management of erectile dysfunction subscribes to a single etiology, i.e. the mechanism of erection. A large number of pharmacological agents are orally consumed and vasoactive agents inserted intraurethrally or injected intrapenially to regain good erection. Modern phytochemicals have been developed from traditional herbs. Phytochemicals focus their mechanism of healing action of the root cause, i.e. the inability to control the proper function of the whole body system. Hence phytochemicals manage erectile dysfunction in the frame of sexual dysfunction as a whole entity. Protodioscin is a phytochemical agent derived from Tribulus terrestris L plant, which has been clinically proven to improve sexual desire and enhance erection via the conversion of protodioscin to DHEA (Dehydroepiandrosterone). Preliminary observations suggest that Tribulus terrestris L grown on different soils does not consistently produce the active component protodioscin. Further photochemical studies of many other herbal plants are needed to explain the inconsistent result found with other herbal plants, such as in diversities of Ginseng, Eurycoma longifolia, Pimpinella pruacen, Muara puama, Ginkgo biloba, Yohimbe etc.
6. R. Estrada-Reyes a, M.Carro-Jua´rez b, L.Martı´nez-Mota – Pro-sexual effects of Turnera diffusa Wild (Turneraceae)in male rats involves the nitric oxide pathway
Ethnopharmacological relevance: Turnera diffusa Wild has been used in folk medicine by its aphrodisiac and tranquilizing properties. Previously, we experimentally showed the aphrodisiac effect of a chemically characterized aqueous extract of Turnera diffusa in male rats. However, the mechanism of action underlying such effects has not been studied. Study aims: As part of our systematic studies of pharmacological properties of Turnera diffusa, we aimed to analyze whether the increased sexual motivation and the augmented sexual performance of sexually sluggish (SL)male rats treated with Turnera diffusa involves the NO pathway. Additionally, we analyzed whether such effects were exerted at the level of the brain or the spinal cord. Finally, anxiety levels and ambulatory activity were also evaluated. Material and methods: Turnera diffusa (10–40 mg/kg) and sildenafil citrate ( 10 mg/kg) with or without a non specific inhibitor of NO synthase, No-nitro-L-arginine methyl esther (L-NAME, 12.5mg/kg)were evaluated in SL rats, in a standard sexual behavior test and in the fictive ejaculation model in spinal cord transected and urethane-anaesthetized SL rats. Anxiety levels or ambulation were assessed in the burying behavior and open-field tests.
Results: Turnera diffusa and sildenafil (both at 10 mg/kg) facilitated expression of male sexual behavior by shortening mainly ejaculation latency. Treatments also facilitated the number of discharges in the ejaculatory motor pattern as well as the number of ejaculatory motor patterns and its associated penile erections. L-NAME prevented the pro-sexual effects of treatments on both experimental models. Besides, the extract of Turnera diffusa (10 mg/kg) produced an anxiolytic-like effect in male rats without affecting ambulation.
Conclusions: Findings from the present work support the notion that pro-sexual effect of the aqueous extract of Turnera diffusa in rats involves the participation of NO path way, mainly at central level. The anxiolytic-like effect of Turnera diffusa is an advantage to its use for improving sexual performance.
7. Ude, C., Schubert-Zsilavecz, M. and Wurglics, M. – Ginkgo biloba Extracts: A Review of the Pharmacokinetics of the Active Ingredients. Clinical Pharmacokinetics (2013) 52: 727.
Ginkgo biloba is among the most favourite and best explored herbal drugs. Standardized extracts of Ginkgo biloba represent the only herbal alternative to synthetic antidementia drugs in the therapy of cognitive decline and Alzheimer’s diseases. The clinical efficiency of such standardized Ginkgo biloba extracts (GBE) is still controversial, but authors of numerous international clinical studies recommended the use of GBE in the described therapies.Extracts of Ginkgo biloba are a mixture of substances with a wide variety of physical and chemical properties and activities. Numerous pharmacological investigations lead to the conclusion that the terpene trilactones (TTL) and the flavonoids of GBE are responsible for the main pharmacological effects of the extract in the therapy of cognitive decline. Therefore, the quality of GBE products must be oriented on a defined quantity of TTL and flavonoids. Furthermore, because of their toxic potential the amount of ginkgolic acid should be less than 5 ppm.However, data on pharmacokinetics and bioavailability, especially related to the central nervous system (CNS), which is the target tissue, are relatively rare. A few investigations characterize the TTL and flavonoids of Ginkgo biloba pharmacokinetically in plasma and in the brain. Recent investigations show that significant levels of TTL and Ginkgo biloba flavonoids cross the blood-brain barrier and enter the CNS of rats after oral application of GBE. Knowledge about the pharmacokinetic behaviour of these substances is necessary to discuss the pharmacological results on a more realistic basis.
8. R. Estrada-Reyesb, P. Ortiz-Lópeza, J. Gutiérrez-Ortíza, L. Martínez-Mota – Turnera diffusa Wild (Turneraceae) recovers sexual behavior in sexually exhausted males (2009)
Ethnopharmacological relevance: In folk medicine, Turnera diffusa Wild (Turnera diffusa, Turneraceae) is considered as an aphrodisiac, but its ability to restore copulation in sexually inhibited subjects has not been reported.
Aim of the study: To determine whether Turnera diffusa recovers sexual behavior in sexually exhausted (SExh) male rats and to identify the main components in an aqueous extract.
Materials and methods: SExh males were treated with Turnera diffusa, 20–80 mg/kg, yohimbine, 2 mg/kg, or vehicle.
Results: Yohimbine and Turnera diffusa (80 mg/kg) significantly increased the percentage of males achieving one ejaculatory series and resuming a second one. In addition, Turnera diffusa significantly reduced the post-ejaculatory interval. These effects were not associated to an increase in locomotor activity or anxiety like behaviors. The HPLC–ESI-MS analysis showed the presence of caffeine, arbutine, and flavonoids as the main compounds in the active extract.
Conclusion: The results support the use of Turnera diffusa as an aphrodisiac in traditional medicine and suggest possible therapeutic properties of Turnera diffusa on sexual dysfunction. The flavonoids present in active extract may participate in its pro-sexual effect, which is analogous to those produced by yohimbine, suggesting a shared mechanism of action.
9. Ganzera M1, Bedir E, Khan IA. – Determination of steroidal saponins in Tribulus terrestris by reversed-phase high-performance liquid chromatography and evaporative light scattering detection.
This paper describes the first analytical method suitable for the determination of steroidal saponins in Tribulus terrestris. A separation by high performance liquid chromatography (HPLC) was achieved by using a reversed-phase (RP-18) column, evaporative light scattering (ELS) detection, and a water/acetonitrile gradient as the mobile phase. The marker compound, protodioscin, was detected at a concentration as low as 10.0 microg/mL. Several different samples of plant material were successfully analyzed, and depending on origin and plant part used for extraction, significant differences in the composition of the saponins were observed. The analysis of market products showed considerable variations of 0.17 to 6.49% in the protodioscin content.
10. Dragomir Dinchev, Bogdan Janda, Liuba Evstatieva, Wieslaw Oleszek, Mohammad R. Aslani, Ivanka Kostova – Distribution of steroidal saponins in Tribulus terrestris from different geographical regions
The steroidal saponins of Tribulus terrestris L. (Zygophyllaceae) are considered to be the factor responsible for biological activity of products derived from this plant. The activity depends on the concentration and the composition of active saponins, which in turn is influenced by the geographical origin of plant material. Samples of T. terrestris collected in Bulgaria, Greece, Serbia, Macedonia, Turkey, Georgia, Iran, Vietnam and India were analyzed by LC-ESI/MS/MS for the presence and the concentration of protodioscin (1), prototribestin (2), pseudoprotodioscin (3), dioscin (4), tribestin (5) and tribulosin (6). The flavonoid rutin (7) was also included in the comparison. The results revealed distinct differences in the content of these compounds depending on region of sample collection, plant part studied and stage of plant development. The samples from Bulgaria, Turkey, Greece, Serbia, Macedonia, Georgia and Iran exhibited similar chemical profile and only some quantitative difference in the content of 1-7 with protodioscin (1) and prototribestin (2) as main components. The Vietnamese and Indian samples exhibit totally different chemical profile. They lack 2 and 5, while tribulosin (6) is present in high amounts. Compounds different from 1 to 7 are dominating in these 3 samples. The presented results suggested the existence of one chemotype common to the East South European and West Asian regions. Most probably, the Vietnamese and Indian samples belong to other chemotypes which are still to be studied and characterized. No clear correlation between the burrs morphology and the chemical composition of the samples has been found.
11. Akhtari, E., Raisi, F., Keshavarz, M., Hosseini, H., Sohrabvand, F., Bioos, S., Kamalinejad, M. and Ghobadi, A. – Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo - controlled study. Daru (2014) 22: 40.
Tribulus terrestris as a herbal remedy has shown beneficial aphrodisiac effects in a number of animal and human experiments. This study was designed as a randomized double-blind placebo-controlled trial to assess the safety and efficacy of Tribulus terrestris in women with hypoactive sexual desire disorder during their fertile years. Sixty seven women with hypoactive sexual desire disorder were randomly assigned to Tribulus terrestris extract (7.5 mg/day) or placebo for 4 weeks. Desire, arousal, lubrication, orgasm, satisfaction, and pain were measured at baseline and after 4 weeks after the end of the treatment by using the Female Sexual Function Index (FSFI). Two groups were compared by repeated measurement ANOVA test. Thirty women in placebo group and thirty women in drug group completed the study. At the end of the fourth week, patients in the Tribulus terrestris group had experienced significant improvement in their total FSFI (p < 0.001), desire (p < 0.001), arousal (p = 0.037), lubrication (p < 0.001), satisfaction (p < 0.001) and pain (p = 0.041) domains of FSFI. Frequency of side effects was similar between the two groups. Tribulus terrestris may safely and effectively improve desire in women with hypoactive sexual desire disorder. Further investigation of Tribulus terrestris in women is warranted.
12. Mameri Filho J, Haidar MA, Soares Junior JM, Baracat EC. – Effects of the association of estrogen and androgen in postmenopausal women. Rev Bras Ginecol Obstet (2005) 27: 118.
To evaluate the effects of the association of estrogen and androgen on the quality of life and sexuality of women during climacterium. Ninety-six postmenopausal women with vasomotor symptoms and sexual dysfunction were included. The participants were randomly divided into three treatment groups with 32 pacients each: placebo, conjugated equine estrogens (CEE) (0.625 mg per day) and CEE (0.625 mg per day) associated with methyltestosterone (2.5 mg per day). The length of the treatment period was three months. The Women Health Questionnaire (WHQ) and the Modified Sexuality Questionnaire were applied to evaluate the quality of life and sexuality before and after the treatment. Some parameters of cardiovascular risk, endometrial echo and hepatic toxicity were evaluated. ANOVA was used for data analysis followed by the Fisher test and the Shapiro-Wilk post hoc test. The improvement in WHQ parameters was significant in the hormonal treatment groups (CEE and CEE + methyltestosterone) compared to the placebo group. However, there were no differences in somatic symptoms among the three groups. The association of estrogen with androgen significantly improved sexual function (score (mean): 64 vs 67, p<0.05) and depressive humor (score (mean): 75 vs 80, p<0.05) compared to estrogen alone. This therapy also presented a large number of WHQ questions with a high score (p<0.05). The use of CEE associated with methyltestosterone decreased the total cholesterol (212±42 and 194±43, before and after the treatment, respectively) and HDL colesterol (56±16 and 48±14, before and after the treatment, respectively), and slightly increased the endometrial echo (4.7±2.3 and 5.5±2.3, before and after the treatment, respectively). No signifcant changes in liver enzymes during the treatment period was detected. Estrogen associated with methyltestosterone resulted in significant improvement in the quality of life and sexuality of postmenopausal women. This effect was superior to estrogen alone and placebo. The effect of treatment with the estrogen-androgen association was evident regarding depressive humor and sexual function questions of the WHQ.
13. K. Milasius, R. Dadeliene, Ju. Skernevicius – The influence of the Tribulus terrestris extract on the parameters of the functional preparadness and athletes organism homeostase
The influence of the Tribulus terrestris extract on the parameters of the functional preparadness and athletes’ organism homeostase was investigated. It was established the positive impact of dietary supplement “Tribulus” (Optimum Nutrition, U.S.A.) using per 1 capsule 3 times a day during 20 days on athletes’ physical power in various energy producing zones: anaerobic alactic muscular power and anaerobic alactic glycolytic power statistically reliable increased. Tribulus terrestris extract, after 20 days of consuming it, did not have essential effect on erythrocytes, haemoglobin and thrombocytes indices. During the experimental period statistically importantly increased percentage of granulocytes and decreased percentage of leucocytes show negative impact of this food supplement on changes of leucocytes formula in athletes’ blood. Creatinkinase concentration in athletes’ blood statistically importantly has increased and creatinine amount has had a tendency to decline during 20 days period of consuming Tribulus terrestris extract. The declining tendency of urea, cholesterol and bilirubin concentrations has appeared. The concentration of blood testosterone increased statistically reliable during the first half (10 days) of the experiment; it did not grow during the next 10 days while consuming Tribulus still.
|*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.|